1. Jeyasimman D, Ercan B*, Dharmawan D*, Naito T, Sun J, and Saheki Y** (2021). PDZD-8 and TEX-2 regulate endosomal PI(4,5)P2 homeostasis via lipid transport to promote embryogenesis in C. elegans. Nature Communications. 12: 6065. PMID: 34663803. Featured in "Editor's Highlights". *Equal contribution. **Corresponding author.
2. Kinnebrew M, Luchetti G, Sircar R, Frigui S, Viti LV, Naito T, Beckert F, Saheki Y, Siebold C, Radhakrishnan A, and Rohatgi R (2021). Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes. eLife. 10: e70504 DOI: 10.7554/eLife.70504
3. Sun J*, Harion R*, Naito T, and Saheki Y** (2021). INPP5K and Atlastin-1 maintain the nonuniform distribution of ER-plasma membrane contacts in neurons. Life Science Alliance. 4: e202101092. PMID: 34556534 *Co-first authors. **Corresponding author.
4. Ercan B*, Naito T*, Koh DHZ, Dharmawan D, and Saheki Y** (2021). Molecular basis of accessible plasma membrane cholesterol recognition by the GRAM domain of GRAMD1b. EMBO J. 40: e106524. PMID: 33604931. *Co-first authors. **Corresponding author.
5. Naito T, Ercan B, Krshnan L, Triebl A, Koh DHZ, Wei FY, Tomizawa K, Torta F, Wenk MR, and Saheki Y* (2019). Movement of accessible plasma membrane cholesterol by GRAMD1 lipid transfer protein complex. eLife. 8: e51401. PMID: 31724953. *Corresponding author. eLife digest
6. Bian X, Saheki Y*, and De Camilli P* (2018). Ca2+ releases E-Syt1 autoinhibition to couple ER-plasma membrane tethering with lipid transport. EMBO J. 37: 219-234. PMID: 29222176. *Corresponding author.
7. Dong R, Saheki Y, Swarup S, Lucast L, Harper JW, and De Camilli P (2016). Endosome-ER contacts control actin nucleation and retromer function through VAP-dependent regulation of PI4P. Cell. 166: 408-423. PMID: 27419871.
8. Saheki Y, Bian X*, Schauder CM*, Sawaki Y, Surma MA, Klose C, Pincet F, Reinisch KM, and De Camilli P (2016). Control of plasma membrane lipid homeostasis by the extended synaptotagmins. Nat Cell Biol. 18: 504-15. PMID: 27065097. News and Views in Nat Cell Biol. 18: 461-3. Recommended in Faculty 1000. *Equal contribution.
9. Fernández-Busnadiego R*, Saheki Y*, and De Camilli P (2015). Three dimensional architecture of extended synaptotagmin-mediated ER-plasma membrane contact sites. Proc Natl Acad Sci U S A. 112: E2004-13. PMID: 25787254. Commentary in Proc Natl Acad Sci U S A. 112: 4837-8. *Co-first authors.
10. Schauder CM, Wu X*, Saheki Y*, Narayanaswamy P, Torta F, Wenk MR, De Camilli P, and Reinisch KM (2014). Structure of a lipid-bound extended-synaptotagmin indicates a role in lipid transfer. Nature. 510: 552-5. PMID: 24847877. Recommended in Faculty 1000. *Equal contribution.
11. Giordano F*, Saheki Y*, Idevall-Hagren O, Colombo S, Pirruccello M, Milosevic I, Gracheva EO, Sviatoslav BN, Borgese N, and De Camilli P (2013). PI(4,5)P2 dependent and Ca2+-regulated ER-plasma membrane interactions mediated by the extended synaptotagmins. Cell. 153: 1494-509. PMID: 23791178. Preview in Cell. 153: 1423-1424. Recommended in Faculty 1000. *Co-first authors. 12. Saheki Y, and Bargmann CI (2009). Presynaptic CaV2 calcium channel traffic requires CALF-1 and the alpha (2) delta subunit UNC-36. Nat Neurosci. 12: 1257-65. PMID: 19718034. News and Views in Nat Neurosci. 12: 1213-4. Recommended in Faculty 1000.
Review Articles
1. Koh DHZ, and Saheki Y* (2021). Regulation of plasma membrane sterol homeostasis by non-vesicular lipid transport. Contact (Thousand Oaks). 4: 1-17. http://doi.org/10.1177/25152564211042451. *Corresponding author.
4. Saheki Y*, and De Camilli P* (2017). Endoplasmic reticulum - plasma membrane contact sites. Annu Rev Biochem. 86: 659-684. PMID: 28301744. *Corresponding author.
5. Saheki Y*, and De Camilli P* (2017). The extended-synaptotagmins. Biochim Biophys Acta Mol Cell Res. 1864: 1490-1493. PMID: 28363589. *Corresponding author. Cover Article.
Book Chapters
1. Saheki Y* (2017) . Endoplasmic reticulum - plasma membrane crosstalk mediated by the extended synaptotagmins. Organelle Contact Sites - From Molecular Mechanism to Disease, Chapter 6 (83-93) Springer Press. Adv Exp Med Biol.997: 83-93. PMID: 28815523. *Corresponding author.
2. Saheki Y, and De Camilli P (2012). Synaptic vesicle endocytosis. The Synapse, Chapter 5 (79-108) Cold Spring Harbor Lab Press. 4: a005645. PMID: 22763746. Cover article.
Other Peer-reviewed Publications
1. Zhang D, Saheki Y, Hu J, and Kornmann B. (2021). Editorial: Coupling and Uncoupling: Dynamic Control of Membrane Contacts. Front. Cell Dev. Biol. 9: 721546. PMID: 34504844.
2. Levine T, Perez Franck, Saheki Y, and Julia von Blume (2019). Meeting Report From the 2019 “Organelle Zone” Symposium in Osaka, Japan. Contact (Thousand Oaks). 2: 2515256419877091. PMID: 31588423.
3. Huang YC, Pirri J, Rayes D, Gao S, Mulcahy B, Grant J, Saheki Y, Francis M, Zhen M, and Alkema M (2019). Gain-of-function mutations in the UNC-2/CaV2α channel lead to excitation-dominant synaptic transmission in C. elegans. eLife. 8: e45905. PMID: 31364988.
4. Bauer Huang SL, Saheki Y, VanHoven MK, Torayama I, Ishihara T, Katsura I, van der Linden A, Sengupta P, and Bargmann CI (2007). Left-right olfactory asymmetry results from antagonistic functions of voltage-activated calcium channels and the Raw repeat protein OLRN-1 in C. elegans. Neural Dev. 2: 24. PMID: 17986337.
5. Ueki Y, Lin CY, Senoo M, Ebihara T, Agata N, Onji M, Saheki Y, Kawai T, Mukherjee PM, Reichenberger E, and Olsen BR (2007). Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice. Cell. 128: 71-83. PMID: 17218256.
6. Wei FY, Nagashima K, Ohshima T, Saheki Y, Lu YF, Matsushita M, Yamada Y, Mikoshiba K, Seino Y, Matsui H, and Tomizawa K (2005). Cdk5-dependent regulation of glucose-stimulated insulin secretion. Nat Med. 11: 1104-1108. PMID: 16155576.
7. Saheki Y, Li ST, Matsushita M, Wu YM, Cai WH, Wei FY, Lu YF, Moriwaki A, Tomizawa K, and Matsui H (2005). A new approach to inhibiting astrocytic IP3-induced intracellular calcium increase in an astrocyte-neuron co-culture system. Brain Res. 1055: 196-201. PMID: 16099437.
8. Li ST, Matsushita M, Moriwaki A, Saheki Y, Lu YF, Tomizawa K, Wu HY, Terada H, and Matsui H (2004). HIV-1 Tat inhibits long-term potentiation and attenuates spatial learning. Ann Neurol. 55: 362-71. PMID: 14991814.